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The quite unexpected positive cardiorenal outcomes that have emerged from the cardiovascular outcomes trials (CVOTs) with both glucagon like peptide-1 receptors agonists (GLP-1RA) and sodium-glucose co-transporter 2 (SGLT-2) inhibitors have produced a shift of diabetes management from the meticulous glycemic control alone to the simultaneous improvement of CV outcomes

For all other laboratory parameters, such as hematologic, renal urea, creatinine, liver enzymes SGOT, SGTP, alkaline phosphatase, lactate dehydrogenase (LDH), total bilirubin, as well as Na, K, Mg, Zinc, and fasting glucose, there was no difference between placebo and LCLT groups

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Coenzyme Q10, a key component of the mitochondrial electron transport chain, is essential for ATP production and antioxidant protection