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Other risk factors for B12 deficiency are stress, excessive alcohol use, and smoking

This clearance process happens in the liver through a two-step metabolic pathway

Cysteine is synthesized via the transsulfuration pathway, in which homocysteine is first converted to cystathionine by cystathionine-beta-synthase (CBS) and subsequently to cysteine

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Zhang D., Du J., Tang C., Huang Y., Jin H