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MC1 Receptor (Melanocortin 1 Receptor) Stimulates melanogenesis: Activation of MC1 on skin melanocytes increases cAMP and activates tyrosinase, resulting in enhanced eumelanin (dark pigment) synthesis and visible skin darkening (tanning) 1

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The patients were OCD patients between the ages of 18-65 and had no psychiatric comorbidities other than MDD

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