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For example, smoking during pregnancy is associated with an increased risk of fetal growth restriction, premature birth and low birthweight, though it has also been linked to a reduced risk of preeclampsia (high blood pressure during pregnancy)

After 85, screenings arent recommended as the potential risks can outweigh the potential benefits

Collectively, these two transitions are necessary for the overall initiation process, which involves transition from never combustible cigarette smoker to established or regular cigarette use (i.e., not merely temporary experimentation that does not progress to regular smoking)