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Hours after the initial trigger, mast cells produce and secrete certain chemokines (TNF, CCL2, CCL8) and renin.[ref] The different mediators released can lead to different symptoms of mast cell activation syndrome: Histamine leads to headaches, migraines, low blood pressure, itching, stomach acid release (and much more) Tryptase causes inflammation and fibrinogen lysis

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Abbreviations LD: Learning disabilities DHA: Docosahexaenoic acid PUFA: Polyunsaturated fatty acid ADHD: Attention deficit hyperactivity disorder NHANES: National Health and Nutrition Examination Surveys NCHS: National Centers for Health Statistics CDC: Centers for Disease Control and Prevention BMI: Body mass index FFQ: Food frequency questionnaire PIR: Poverty-to-income ratio MEC: Mobile examination center ORs: Odds ratios CIs: Confidence intervals RCT: Randomized controlled trial ROS: Reactive oxygen species References Cavendish W