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Anagen/catagen classification was performed according to previously established morphological criteria reported in prior human hair follicle organ culture studies [14]: in the fully mature anagen VI stage, terminal hair follicles are characterized by a well-defined, onion-like hair bulb and a slim, elongated dermal papilla

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This syndrome has been reported to be more likely if the patient has abnormal kidney function.9 Although there is some significant debate on this point10, it is generally agreed that patients with abnormal kidney function should start allopurinol at low doses and build up, to ensure that the allopurinol is effectively excreted