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doi: 10.1007/s11033-020-05590-5 Summary Keywords antidepressant effects, Ashwagandha, depressive disorder, Rhodiola, supplements Citation Li X, Li X, Li Y, Liu Z, Cai Y, Yao Q, Zhao S and Yu Q (2026) Rhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders

PMID:19393193

It is necessary to expand extensive chronic clinical trials to evaluate the long-term safety, efficacy, and optimal dosing of polyphenols, examine gene-diet and microbiota-polyphenol interactions to elucidate inter-individual variability, develop innovative delivery systems to improve bioavailability and facilitate clinical translation, and clarify potential drug interactions and safety in vulnerable populations

Chem Soc Rev 1:233262