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Additional details regarding all the C p HMD parametrizations and simulations performed are provided in the Supplementary Methods section and in Supplementary Tables 1 and 2

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The concentrations are: 0.25 mg/0.5 mL (0.5 mg/mL) 0.5 mg/0.5 mL (1 mg/mL) 1 mg/0.5 mL (2 mg/mL) 1.7 mg/0.75 mL (2.27 mg/mL) 2.4 mg/0.75 mL (3.2 mg/mL) Important safety consideration : Patients should never attempt to measure semaglutide doses by volume or extract medication from pens using syringes

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