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5 Potential oxidative stress-related therapeutic targets in gastric cancer Regulation of redox homeostasis is crucial because increasing oxidative stress has a role in all stages of carcinogenesis either initiating/stimulating tumorigenesis and promoting cancer cells transformation/proliferation or leading to cell death

The extensive glycosylation of the mucins means that they are highly hydrophilic and help to maintain the mucus as a gel-like fluid (Crouzier et al., 2015)

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