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In populations who cannot exercise due to frailty, physical disability, or cardiovascular limitations, MOTS-c represents one of the most compelling candidates in the emerging class of pharmacological exercise mimetics

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These symptoms are often motor abnormalities associated with cerebellar or extrapyramidal injury.26 They may include tremor, coordination defects, dystonia, or choreiform movements.2729 Sensory function and intelligence are generally unaffected in Wilsons disease

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