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In its Acceleration Plan to Stop Obesity, adopted in 2022, WHO highlights many different factors contribute to obesity and that the matter is not just a matter of individual responsibility

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Key benefits for perimenopausal women: Restores sexual desire through a non-hormonal brain pathway, reaching neurological deficits that HRT alone does not address May improve mood and overall sense of energy via dopamine activation, countering mood disruption from progesterone fluctuations No interaction with hormone replacement therapy is documented in available prescribing information

doi: 10.1016/j.clim.2011.04.005