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LK: Conceptualization, Supervision, Writing original draft, Data curation, Software

Data availability The TCGA RNA-seq gene expression data were downloaded from The Cancer Genome AtlasData Portal The RNA-seq data of different human liver cancer cell lines were downloaded from Broad Institute Cancer Cell Line Encyclopedia (CCLE, file name: CCLE_RNAseq_rsem_genes_tpm_20180929.txt.gz) and from Liver Cancer Model Repository (LIMORE, download link: Gene expression profiles of 81 cell lines)

leaf extract enhances stress tolerance and promotes healthy longevity through HLH-30/TFEB, DAF16/FOXO, and SKN1/NRF2 crosstalk in Caenorhabditis elegans